HDAC/BET-IN-1

SKU: orb1744608

Description

HDAC/BET-IN-1 is a dual-acting inhibitor targeting histone deacetylases (HDAC1/6) and bromodomain protein BRD4 with submicromolar potency. It demonstrates significant antileukemic activity in cellular assays, making it a valuable chemical probe for oncology research, particularly in studying epigenetic pathways and their role in hematological malignancies.

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 2757573-68-3
• MW: 604.71
• Formula: C₂₉H₄₀N₄O₈S
• SMILES: CC1=C2C(=C(N1)C(=O)NC3=C(C=CC(=C3)S(=O)(=O)N4CCOCC4)OCCCCCCCC(=O)NO)CCCCC2=O
• Target: HDAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162641035