HDAC1/2 and CDK2-IN-1

SKU: orb1686831

Description

HDAC1/2 and CDK2-IN-1 (compound 14d) is a dual-acting inhibitor targeting HDAC1, HDAC2, and CDK2 with IC50 values of 70.7, 23.1, and 0.80 μM, respectively. It induces cell cycle arrest and apoptosis, demonstrating anti-tumor efficacy in both cellular assays and in vivo models, making it a useful probe for oncology and epigenetics research.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 2418559-01-8
• MW: 483.95
• Formula: C₂₆H₂₂ClN₇O
• SMILES: C(N1C=2C(=C(NC3=CC=C(C)C=C3)N=C(Cl)N2)N=C1)C4=CC=C(C(NC5=C(N)C=CC=C5)=O)C=C4
• Target: Apoptosis,Others,HDAC,CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162674387