HDAC1-IN-4

SKU: orb1686560

Description

HDAC1-IN-4 is a potent and selective inhibitor of Plasmodium falciparum histone deacetylase 1 (PfHDAC1), exhibiting potent antimalarial activity with an IC50 below 5 nM. This compound demonstrates low cytotoxicity and is a valuable chemical probe for investigating epigenetic mechanisms in malaria parasite biology, supporting both in vitro and in vivo antimalarial research.

Research Area

Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 2482998-39-8
• MW: 507.82
• Formula: C₂₁H₂₄BrClN₆O₂
• SMILES: Cl.Cn1cc(CN2CC3(C2)CCN(C3)c2ncc(cn2)C(=O)NO)c2ccc(Br)cc12
• Target: Others,HDAC,Parasite

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163196372