hAChE-IN-10

SKU: orb2945213

Description

hAChE-IN-10 (ET11) is a potent, nanomolar-range human AChE inhibitor with additional antioxidant and metal-chelating properties. It inhibits Cu2+-induced Aβ aggregation in vitro and has demonstrated in vivo efficacy by reducing amyloid pathology and improving cognition in scopolamine-impaired mouse models.

Research Area

Neuroscience

Key Properties

• CAS Number: 3058182-98-9
• MW: 494.948
• Formula: C₂₅H₂₄ClFN₆O₂
• SMILES: O=C(NCCCNC=1C=2C=CC(Cl)=CC2N=C3C1CCCC3)C4=NN(C(O)=C4)C5=NC=C(F)C=C5
• Target: Beta Amyloid,Cholinesterase (ChE)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677440