H-9 dihydrochloride

SKU: orb1704489

Description

H-9 dihydrochloride

Research Area

Cardiovascular Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 116700-36-8
• MW: 324.23
• Purity: 97.30%
• Formula: C₁₁H₁₅Cl₂N₃O₂S
• SMILES: O=S(NCCN)(C1=CC=CC2=C1C=CN=C2)=O.Cl.Cl
• Target: EGFR,PKA,5-HT Receptor
• Solubility: DMSO:Soluble

Bioactivity

• In Vivo:
  Microperfusing H-9 Dihydrochloride (100 μM) prevents picrotoxin seizures in 50% of the animals and significantly reduces the mean number of seizures and mean seizure duration.
• In Vitro:
  Significantly inhibiting A431 cells, H-9 Dihydrochloride is more effective at inhibiting cyclic nucleotide-dependent protein kinases than other kinases.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

5-HT, 5HTReceptor, 5HT Receptor, H9, H-9, H9 Dihydrochloride, H9 dihydrochloride, H-9 Dihydrochloride, H 9, H 9 Dihydrochloride, H 9 dihydrochloride, EGFR, PKA

Compound Identifiers

PubChem CID

11957465