Guajadial B

SKU: orb1682462

Description

Guajadial B is a catalytic inhibitor of Topoisomerase I (Top1) that mitigates DNA damage induced by Top1 poisons. It exhibits potent cytotoxicity across multiple human cancer cell lines, with an IC50 of 150 nM in A549 lung carcinoma cells, supporting its investigation as an anticancer agent in biochemical and cellular research.

Research Area

Molecular Biology

Key Properties

• CAS Number: 1414455-03-0
• MW: 474.597
• Formula: C₃₀H₃₄O₅
• SMILES: C\C1=C/CC(C)(C)\C=C\C[C@@]2(C)Oc3c(C=O)c(O)c(C=O)c(O)c3[C@H]([C@@H]2CC1)c1ccccc1
• Target: Topoisomerase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

137346032