GS-443902

SKU: orb1984329

Description

GS-443902, the active triphosphate metabolite of Remdesivir, is a potent viral RNA-dependent RNA polymerase (RdRp) inhibitor. It demonstrates in vitro activity against viruses like RSV and HCV with IC50 values of 1.1 µM and 5 µM, respectively, supporting antiviral research in biochemical and cell-based assays.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Protein Biochemistry

Key Properties

• CAS Number: 1355149-45-9
• MW: 531.2
• Formula: C₁₂H₁₆N₅O₁₃P₃
• SMILES: Nc1ncnn2c(ccc12)[C@@]1(O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O)C#N
• Target: Nucleoside Antimetabolite/Analog|||DNA/RNA Synthesis|||Drug Metabolite|||HCV Protease|||RSV|||SARS-CoV

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

56832906