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Gramicidin S
Catalog Number: orb2277088
| Catalog Number | orb2277088 |
|---|---|
| Category | Small Molecules |
| Description | Gramicidin S (Gramicidin Soviet), a cationic cyclic peptide antibiotic, disrupts the membrane integrity of both Gram-positive and Gram-negative bacteria and inhibits cytochrome bd quinol oxidase. |
| MW | 1141.45 |
| CAS Number | 113-73-5 |
| Formula | C60H92N12O10 |
| SMILES | O=C1N2[C@](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC3=CC=CC=C3)C(=O)N4[C@](C(=O)N[C@@H]([C@@H](C)C)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]1CC5=CC=CC=C5)(CCC4)[H])(CCC2)[H] |
| Storage | -20°C |
| Research Area | Infectious Disease & Virology |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Gramicidin [orb1226342]
>98%(HPLC)
1405-97-6
1882.3
C99H140N20O17
100 mg, 200 mg, 25 mg, 50 mg, 1 g, 500 mg
For example, if the dosage of your experiment is 10mg/kg, the weight of each animal is 50g, and the volume of the dosing is 100μL, then the working solution concentration of your experiment is 5mg/mL. If the formula you used is 5% DMSO+ 30% PEG300+ 5% Tween 80 + 60% Saline/PBS/ddH2O, the preparation method is as follows:
Mother liquor preparation method: 5mg of drug dissolved in 100μL DMSO (mother liquor concentration is 50mg/mL). Preparation method of in vivo formulation: For 1mL of working solution preparation, take 50μL of DMSO mother liquor, add 300 μL of PEG300 to mix well and clarify, then add 50μL of Tween-80 to mix well and clarify, and finally add 600μL of Saline/PBS/ddH2O to mix well and clarify.Note:
- For Reference Only. Please choose the appropriate dissolution protocol according to your experimental animal and administration method.
- We suggest that in cell experiments, the final concentration of DMSO is not more than 0.1%, in animal experiments, for healthy mice, the final concentration of DMSO is not more than 10%; For nude or frail mice, the final concentration of DMSO is not more than 2%.
