GR–14-3-3 stabilizer-1

SKU: orb2945662

Description

GR-14-3-3 stabilizer-1 (compound 10) is a molecular glue that stabilizes glucocorticoid receptor (GR) by disrupting its interaction with 14-3-3 proteins. This tool compound is used in vitro and in vivo to study GR signaling, protein-protein interactions, and the therapeutic potential of molecular glues in diseases like inflammation and cancer.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 271798-59-5
• MW: 317.793
• Formula: C₁₅H₁₂ClN₃OS
• SMILES: O=C1NN=C(N1C=2C=CC=CC2)CSC3=CC=C(Cl)C=C3
• Target: Molecular Glues

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

2824787