Gnetol

SKU: orb1300109

Description

Gnetol is a bioactive small molecule that potently inhibits butyrylcholinesterase (IC50: 1.3 µM) and murine tyrosinase, suppressing melanin synthesis in B16 melanoma cells. It also inhibits arachidonic acid-induced platelet aggregation, making it relevant for neurological, dermatological, and cardiovascular research.

Research Area

Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Neuroscience, Protein Biochemistry

Key Properties

• CAS Number: 86361-55-9
• MW: 244.24
• Purity: 99.21% (May vary between batches)
• Formula: C₁₄H₁₂O₄
• SMILES: Oc1cc(O)cc(\C=C\c2c(O)cccc2O)c1
• Target: COX|||Tyrosinase|||AChR|||HDAC
• Solubility: DMSO:100 mg/mL (409.43 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (20.47 mM)

Bioactivity

• Target IC50:
  COX-1:0.78 μM|Tyrosinase:4.5 μM|BChE:1.3 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

COX, Cyclooxygenase, BChE, antinociceptive, antihepatotoxic, anticancer, antidiabetic, Antioxidant, antiproliferative, Gnetol, Inhibitor, hepatoprotective, HDAC, Histone deacetylases, melanin, inhibit, TGF-β, Tyrosinase, PPARα

Compound Identifiers

PubChem CID

45382232