GNA002

SKU: orb1709574

Description

GNA002 is a covalent and highly selective small molecule inhibitor of EZH2 with an IC50 of 1.1 µM. It is a valuable chemical probe for investigating the role of EZH2-mediated histone methylation in oncology and epigenetics research, applicable in both cellular and animal studies.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 1385035-79-9
• MW: 701.89
• Formula: C₄₂H₅₅NO₈
• SMILES: [H][C@@]12C[C@@]3([H])C=C4C(=O)c5c(O)c(C\C=C(/C)CCC=C(C)C)c(O)c(CC=C(C)C)c5O[C@@]14[C@@](C\C=C(\C)C(=O)NCCOCC)(OC2(C)C)C3=O
• Target: Histone Methyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138911304