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GK730

SKU: orb3173894

Description

GK730 is a potent and selective inhibitor of the SARS-CoV-2 main protease, with an IC50 value of 5.75 nM. It does not inhibit cathepsin B and shows weak inhibition of cathepsin L (IC50 of 11 μM). GK730 effectively blocks both viral replication and the entry pathways of variants like Omicron. In Vero E6 cells, the EC50 value for wild-type SARS-CoV-2 is 5.70 μM, with a CC50 value greater than 100 μM. GK730 is applicable for COVID-19 research.

Images & Validation

Key Properties

TargetSARS-CoV

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information