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GK718

SKU: orb1942453

Description

GK718 is a selective HDAC1/3 inhibitor (IC50: HDAC1=259 nM, HDAC3=139 nM) that increases acetylated histone H3 levels in cellular assays. It has demonstrated efficacy in an in vivo model, reducing Bleomycin-induced pulmonary fibrosis in mice, supporting research in epigenetics and fibrotic diseases.

Research Area

Epigenetics & Chromatin, Molecular Biology

Images & Validation

Key Properties

TargetHDAC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information