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Giredestrant

SKU: orb1218533

Description

Giredestrant potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity. Giredestrant, a non-steroidal ER ligand, is an orally active and selective estrogen receptor (ER) antagonist.

Images & Validation

Key Properties

CAS Number1953133-47-5
MW522.55
Purity>98% (HPLC)
FormulaC27H31F5N4O
SMILESC[C@H](Cc1c2[nH]c3c1cccc3)N(CC(CO)(F)F)[C@@H]2c(c(F)cc(NC1CN(CCCF)C1)c1)c1F
TargetEstrogen Receptor/ERR
SolubilityDMSO:100mg/mL (191.37 mM; Need ultrasonic)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

GDC-9545

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Giredestrant (orb1218533)

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Available Sizes

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500 mg
2 mg
$ 330.00
5 mg
$ 400.00
10 mg
$ 620.00
25 mg
$ 1,140.00
50 mg
$ 1,800.00
100 mg
$ 2,810.00
200 mg
$ 3,810.00