Ginsenoside Ra1

SKU: orb1297557

Description

Ginsenoside Ra1, a ginseng-derived saponin, potently inhibits protein tyrosine kinase (PTK) activation during hypoxia/reoxygenation (H/R) injury. This activity makes it a valuable research tool for studying cardiovascular and neurological ischemia-reperfusion models in vitro and exploring potential cytoprotective mechanisms.

Research Area

Signal Transduction

Key Properties

• CAS Number: 83459-41-0
• MW: 1211.38
• Purity: 97.44% (May vary between batches)
• Formula: C₅₈H₉₈O₂₆
• SMILES: [H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)CC[C@H](O[C@]4([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@]4([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C)[C@]3([H])CC[C@@]21C)[C@](C)(CCC=C(C)C)O[C@@H]1O[C@H](CO[C@@H]2OC[C@H](O[C@]3([H])OC[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O
• Target: Tyrosine Kinases

Bioactivity

• In Vitro:
  Ginsenoside Ra1 showed significant inhibitory effects on protein tyrosine kinase (PTK) activation induced by an in vitro hypoxia/reoxygenation (H/R) model in cultured human umbilical vein endothelial cells (HUVEC).

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Ginsenoside Ra 1, Ginsenoside Ra1, Ginsenoside Ra-1, Inhibitor, PTK, Tyrosine Kinases, TyrosineKinases

Compound Identifiers

PubChem CID

100941542