Gentamicin

SKU: orb1702241

Description

Gentamicin

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 1403-66-3
• MW: 477.60(Avervage)
• Formula: C₂₁H₄₃N₅O₇
• SMILES: CN[C@@H]1[C@H]([C@H](OC[C@@]1(O)C)O[C@H]2[C@@H](C[C@@H]([C@H]([C@@H]2O)O[C@H]3O[C@@H](CC[C@H]3N)CN)N)N)O.CN[C@@H]4[C@H]([C@H](OC[C@@]4(O)C)O[C@H]5[C@@H](C[C@@H]([C@H]([C@@H]5O)O[C@H]6O[C@H]([C@H](N)C)CC[C@H]6N)N)N)O.CN[C@@H]([C@@H]7CC[C@H]([C@H](O7)O[C@@H]8[C@H](C[C@H]([C@@H]([C@H]8O)O[C@H]9OC[C@](O)([C@@H]([C@H]9O)NC)C)N)N)N)C
• Target: Antibacterial,Antibiotic
• Solubility: H2O:24.83 mg/mL

Bioactivity

• In Vivo:
  in vivo efficacy of oxiconazole and Gentamicin combination in a murine superficial skin infection model the combination of oxiconazole (2%) and Gentamicin (0.1%) reduce the bacterial load in skin by ~2.77 log10 CFU/gm and Gentamicin (~2.06 log10 CFU/gm) alone. These results indicate tha the combination of Oxiconazole with gentamicin is potently active in vivo against S. aureus skin infections.
• In Vitro:
  Gentamicin was dissolved in EMEM and used in a final concentration of 200 μg/ml. All bacterial strains grew in the absence of antibiotics and All were grossly inhibited by Gentamicin. Gentamicin is superior to penicillin and streptomycin for control of bacterial growth in tissue culture. Its superiority in controlling P. aeruginosa, Proteus sp., and S. faecalis organisms. To this list may now be added Bacillus cereus, Klebsiella pneumoniae, Aeromonas, Enterobacter, Serratia, Citrobacter, and Alcaligenes faecalis.

Storage & Handling

• Storage: store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Centicin, antibiotic, Antibacterial, Lyramycin, Oksitselanim, Gentamicin, Refobacin, Septigen

Compound Identifiers

PubChem CID

6713924