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Gefitinib-based PROTAC 3

SKU: orb1225618

Description

Gefitinib-based PROTAC 3 is a VHL-recruiting PROTAC that induces the degradation of EGFR and EGFR mutants with DC50 of 11.7 nM and 22.3 nM for HCC827 cell (Exon 19 del) and H3255 cell (L858R).

Images & Validation

Key Properties

CAS Number2230821-27-7
MW934.5
Purity>98% (HPLC)
FormulaC47H57ClFN7O8S
TargetPROTAC

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

Gefitinib-based PROTAC 3 (orb1225618)

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200 mg
500 mg
2 mg
$ 110.00
5 mg
$ 160.00
10 mg
$ 260.00
25 mg
$ 410.00
50 mg
$ 610.00
100 mg
$ 870.00