GAT1508

SKU: orb1910664

Description

GAT1508 (GAT-1508) is a potent, specific activator for brain-expressed GIRK1/2 channels (EC50=75 nM), specifically activates the brain GIRK1/2 over the cardiac GIRK1/4; GAT1508 is an allosteric modulator of channel–phosphatidylinositol 4,5-bisphosphate interactions. GAT1508 effectively extinguished conditioned fear in rodents and lacked cardiac and behavioral side effects, suggesting its potential for use in pharmacotherapy for post-traumatic stress disorder.

Key Properties

• CAS Number: 2397594-21-5
• MW: 377.258
• Purity: The purity of the compound is 98%
• Formula: C₁₅H₁₃BrN₄OS
• SMILES: C1=CC=CC(N2N=C(C=C2NC(=O)NC2SC(Br)=CC=2)C)=C1

Storage & Handling

• Storage: Store at -20°C (desiccating conditions).
• Disclaimer: For research use only