Gabexate mesylate

SKU: orb1310679

Description

Gabexate mesylate (FOY) is a synthetic serine protease inhibitor that selectively targets thrombin, plasmin, and kallikrein. It is applied in research models of pancreatitis, DIC, and as an experimental anticoagulant, with utility in both in vitro enzymatic assays and in vivo pharmacological studies.

Research Area

Metabolism Research, Protein Biochemistry

Key Properties

• CAS Number: 56974-61-9
• MW: 417.48
• Purity: 99.64% (May vary between batches)
• Formula: C₁₇H₂₇N₃O₇S
• SMILES: CS(O)(=O)=O.CCOC(=O)c1ccc(OC(=O)CCCCCNC(N)=N)cc1
• Target: Serine Protease,Factor Xa,Proteasome
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.79 mM);DMSO:55 mg/mL (131.74 mM);H2O:17.1 mM

Bioactivity

• Target IC50:
  Serine protease:0.19 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Factor Xa, FactorXa, FOY, Gabexate, Gabexate mesylate, Gabexate Mesylate, Fxa, Inhibitor, inhibit, Proteasome, Serine Protease, SerineProtease

Compound Identifiers

PubChem CID

6604561