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GABAA receptor agent 1

SKU: orb1219587

Description

GABAA receptor agent 1 has strong anticonvulsant activity and is a high affinity ligand of GABAA receptor.

Images & Validation

Key Properties

CAS Number1571-87-5
MW273.67
Purity>98% (HPLC)
FormulaC13H8ClN3O2
SMILES[O-][N+](=O)c1ccc2nc([nH]c2c1)-c1ccc(Cl)cc1
TargetGABAA
SolubilityIn Vitro: DMSO : 83.33 mg/mL (304.49 mM)

Bioactivity

In Vivo
GABAA receptor agent 1 (30 mg/kg; intraperitoneal) inhibits the maximum electroshock (MES) and pentylenetetrazole (PTZ)-induced convulsions in swiss albino rats.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

GABAA receptor agent 1 (orb1219587)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

5 mg
$ 190.00
10 mg
$ 290.00
25 mg
$ 540.00
50 mg
$ 790.00
100 mg
$ 1,140.00
500 mg
$ 2,290.00