GA3-AM

SKU: orb1697125

Description

GA3-AM is an acetoxymethyl ester derivative of erythromycin designed to bind the gibberellin receptor GID1. It is utilized as a chemical tool in plant biology research, particularly in studies employing inducible split recombinase systems for investigating gibberellin signaling pathways in vivo and in vitro.

Key Properties

• CAS Number: 1373154-68-7
• MW: 418.44
• Purity: 99.83% (May vary between batches)
• Formula: C₂₂H₂₆O₈
• SMILES: CC(=O)OCOC(=O)[C@H]1[C@@H]2[C@@]3(C)[C@@H](O)C=C[C@@]2(OC3=O)[C@@H]2CC[C@]3(O)C[C@]12CC3=C
• Target: Others
• Solubility: DMSO:1 mg/mL (2.39 mM)

Bioactivity

• In Vitro:
  GA3-AM is a cell-permeable analogue of the plant hormone gibberellic acid, which can be used as a chemical dimerizer or chemical inducer. It has been combined with the rapamycin dimerization system and CRISPR/Cas9 activators to control the timing of CRISPR/Cas9 activator functions, thereby enabling temporal regulation of multiple genes.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

GA3 AM, GA3AM, GA-3-AM, GA3-AM

Compound Identifiers

PubChem CID

124221748