G4/HDAC-IN-1

SKU: orb1744551

Description

G4/HDAC-IN-1 is a dual-targeting small molecule that stabilizes G-quadruplex (G4) structures and inhibits histone deacetylase (HDAC) activity with an IC50 of 1.1 μM. It demonstrates potent anti-proliferative effects in vitro and suppresses tumor growth in triple-negative breast cancer (TNBC) xenograft models, highlighting its utility in oncology research.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Key Properties

• MW: 698.27
• Formula: C₃₆H₄₉ClFN₇O₄
• SMILES: CN(C)CCCNC(=O)C1=CC=C(C=C1)/C=C/2\CCN3C2=NC4=CC(=C(C=C4C3=O)F)N5CCN(CC5)CCCCCCCC(=O)NO.Cl
• Target: Others,DNA/RNA Synthesis,HDAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

165412735