G3-VC-PAB-DMEA-Duocarmycin DM

SKU: orb2564825

Description

Compound LD-1 (G3-VC-PAB-DMEA-Duocarmycin DM) is a duocarmycin-based linker-payload designed for constructing antibody-drug conjugates (ADCs). It enables targeted drug delivery, with its cleavable linker facilitating the release of the potent cytotoxin in cancer cells, as studied in preclinical in vitro and in vivo models for oncology research.

Key Properties

• CAS Number: 2415664-00-3
• MW: 1154.7
• Formula: C₅₆H₇₂ClN₁₃O₁₂
• SMILES: C(Cl)[C@H]1C2=C(N(C(=O)C=3NC=4C(C3)=CC(OCCN(C)C)=CC4)C1)C=C(OC(N(CCN(C(OCC5=CC=C(NC([C@@H](NC([C@@H](NC(CNC(CNC(CN)=O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C5)=O)C)C)=O)C=6C2=CC=CC6
• Target: Drug-Linker Conjugates for ADC

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146556335