FV-100

SKU: orb2655597

Description

FV-100 (Valnivudine, CF-1743) is a potent, selective, bicyclic nucleoside analogue inhibitor of varicella zoster virus (VZV) with EC50 of subnanomolar range in vitro.HSV Infection Phase 3 Clinical.

Key Properties

• CAS Number: 956483-03-7
• MW: 548.077
• Purity: >98% (HPLC)
• Formula: C₂₈H₃₈ClN₃O₆
• SMILES: CCCCCC1=CC=C(C=C1)C2=CC3=CN(C(=O)N=C3O2)C4CC(C(O4)COC(=O)C(C(C)C)N)O.Cl
• Target: HSV
• Solubility: In Vitro: DMSO : 100 mg/mL (187.25 mM)

Bioactivity

• In Vivo:
  FV-100 (50-500 mg/kg; p.o.) does not induce biologically relevant respiratory changes or any apparent neuropharmacological effects in rats.
• In Vitro:
  FV-100 is intensely fluorescent when illuminated by wavelengths of 340-380 nm. FV-100 (1 h) produces a different distribution in HeLa cells.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Valnivudine | FV100 | CF-1743

Quick Database Links

Gene Symbol

HSV