Fumaric acid (Standard)

SKU: orb3025516

Description

Fumaric acid (Standard) is the standard substance of Fumaric acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Fumaric acid (2-Butenedioic acid) attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling. Fumaric acid has recently been identified as an oncometabolite or an endogenous, cancer-causing metabolite. High levels of this organic acid can be found in tumors or biofluids surrounding tumors. Its oncogenic action appears due to its ability to inhibit prolyl hydroxylase-containing enzymes.

Key Properties

• CAS Number: 110-17-8
• MW: 116.07
• Formula: C₄H₄O₄
• SMILES: C(=C/C(O)=O)\C(O)=O
• Target: NF-κB,p38 MAPK,Endogenous Metabolite

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

NF-κB,p38 MAPK,Endogenous Metabolite