Fumaric acid

• Catalog Number: orb1303780
• Category: Small Molecules
• Description: Fumaric acid
• CAS Number: 110-17-8
• Purity: 98%
• MW: 116.07
• SMILES: C(=C/C(O)=O)\C(O)=O
• Formula: C₄H₄O₄
• Biological Activity: Fumaric acid (2-Butenedioic acid) attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling. Fumaric acid has recently been identified as an oncometabolite or an endogenous, cancer-causing metabolite. High levels of this organic acid can be found in tumors or biofluids surrounding tumors. Its oncogenic action appears due to its ability to inhibit prolyl hydroxylase-containing enzymes.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.