FT895

SKU: orb1709665

Description

FT895 is a potent and selective HDAC11 inhibitor with demonstrated antifungal and antitumor properties. In vitro studies show it suppresses HDAC11 expression and restricts EV71 viral replication, supporting its utility in oncology, infectious disease, and epigenetics research.

Research Area

Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 2225728-57-2
• MW: 352.31
• Purity: 96.04% (May vary between batches)
• Formula: C₁₆H₁₅F₃N₄O₂
• SMILES: CC1(C)N(Cc2c1cccc2C(=O)NO)c1cnc(cn1)C(F)(F)F
• Target: HDAC,Antifungal
• Solubility: DMSO:20 mg/mL (56.77 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.68 mM)

Bioactivity

• Target IC50:
  HDAC11:3 nM
• In Vitro:
  FT895 is a highly selective inhibitor of HDAC11, exhibiting over 1000-fold selectivity against the other 10 members of the HDAC family.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

HDAC11, FT 895, FT895, FT-895, Fungal

Compound Identifiers

PubChem CID

134492522