Frataxin-IN-1

SKU: orb2566214

Description

Frataxin-IN-1 is a small molecule inhibitor of the mitochondrial protein frataxin (IC50 = 45 µM). This compound, also known as (+)-11, is a research tool used in Friedreich's ataxia (FRDA) studies to investigate disease mechanisms involving iron-sulfur cluster biogenesis and mitochondrial dysfunction in cellular models.

Research Area

Cell Biology

Key Properties

• CAS Number: 102616-64-8
• MW: 373.4
• Purity: 99.34%
• Formula: C₂₀H₂₃NO₆
• SMILES: OC=1C=C2OCOC2=CC1C(C=3C=CC=C(OC)C3OC)N4CCOCC4
• Target: Ferroptosis,Others
• Solubility: H2O:<1 mg/mL (insoluble);DMSO:100 mg/mL (267.81 mM)

Bioactivity

• Target IC50:
  Frataxin:45 μM

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

343010