FR167344 free base

SKU: orb1989247

Description

FR167344 free base is a potent, orally bioavailable, and selective nonpeptide antagonist of the bradykinin B2 receptor, with an IC50 of 65 nM and no significant affinity for the B1 subtype. It is a valuable research tool for investigating the role of B2 receptors in inflammation, pain, and vascular permeability in both in vitro and in vivo models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 215258-13-2
• MW: 673.38
• Formula: C₃₀H₂₈BrCl₂N₅O₄
• SMILES: O(CC1=C(Cl)C(N(C(CNC(/C=C/C2=CC=C(C(N(C)C)=O)C=C2)=O)=O)C)=CC=C1Cl)C=3C=4N(C(Br)=C(C)N4)C=CC3
• Target: Bradykinin Receptor,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

9810391