Formycin triphosphate

SKU: orb3134467

Description

Formycin triphosphate is a fluorescent analog of ATP, exhibiting enhanced fluorescence when binding to enzyme active sites. It acts as a competitive inhibitor of avian liver pyruvate carboxylase (pyruvate carboxylase). Additionally, formycin triphosphate increases atrial natriuretic factor (ANF)-stimulated guanylate cyclase activity with an EC50 of approximately 90 μM and inhibits ATP-stimulated guanylate cyclase activity with an IC50 of around 100 μM.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 16409-13-5
• MW: 507.18
• Formula: C₁₀H₁₆N₅O₁₃P₃
• SMILES: O[C@H]1[C@H](C=2C=3C(NN2)=C(N)N=CN3)O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@H]1O
• Target: Guanylate cyclase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Guanylate cyclase