Fomepizole

SKU: orb1310313

Description

Fomepizole (4-Methylpyrazole) is a competitive alcohol dehydrogenase inhibitor used as an antidote for methanol and ethylene glycol poisoning. It is widely applied in toxicology research, serving as a critical tool in both in vivo models of poisoning and in vitro enzymatic studies to investigate metabolic pathways and inhibition mechanisms.

Research Area

Metabolism Research, Neuroscience

Key Properties

• CAS Number: 7554-65-6
• MW: 82.1
• Purity: 98.88%
• Formula: C₄H₆N₂
• SMILES: CC1=CNN=C1
• Target: Cytochromes P450,AChR
• Solubility: DMSO:250 mg/mL (3045.07 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (24.36 mM);H2O:100 mg/mL (1218.03 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CAT, Antizol, Antizol-Vet, antidote, 4-Methylpyrazole, ADH, alcohol, dehydrogenase, Cytochrome P450, CYPs, methanol, Inhibitor, inhibit, ethylene, Fomepizole, glycol

Compound Identifiers

PubChem CID

3406