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Fluvastatin

SKU: orb1705076

Description

Fluvastatin is a potent, competitive HMG-CoA reductase inhibitor (IC50: 8 nM) used to lower plasma cholesterol. It also reduces oxidative stress in vascular smooth muscle cells via an Nrf2 pathway, making it a research tool for studying atherosclerosis and cardiovascular disease in both cellular and animal models.

Research Area

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number93957-54-1
MW411.47
Purity98.94% (May vary between batches)
FormulaC24H26FNO4
SMILESC(=C/[C@@H](C[C@@H](CC(O)=O)O)O)\C1=C(C=2C(N1C(C)C)=CC=CC2)C3=CC=C(F)C=C3
TargetHMG-CoA Reductase,Autophagy
SolubilityH2O:Insoluble;DMSO:252.5 mg/mL (613.65 mM)

Bioactivity

Target IC50
HMG-CoA reductase:8 nM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Cranoc, Canef, HMGCoAReductase, HMGCoA Reductase, HMG-CoA Reductase (HMGCR), Lescol, Fluvastatin, Vastin, XU-62320, XU62320, XU 62320

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Quality Guarantee

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Key Properties

No computed properties available.

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Fluvastatin (orb1705076)

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% DMSO +
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% Tween 80 +
%

Available Sizes

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10 mg
$ 70.00
25 mg
$ 90.00
50 mg
$ 110.00
100 mg
$ 130.00
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