Florfenicol

SKU: orb1310597

Description

Florfenicol is a fluorinated thiamphenicol analog approved for treating bovine respiratory disease and foot rot, as well as enteric septicemia in catfish. It is a broad-spectrum antibiotic used in veterinary medicine and aquaculture research, with applications in both in vivo and in vitro studies of bacterial infections.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 73231-34-2
• MW: 358.21
• Purity: 99.33%
• Formula: C₁₂H₁₄Cl₂FNO₄S
• SMILES: [C@@H]([C@H](NC(C(Cl)Cl)=O)CF)(O)C1=CC=C(S(C)(=O)=O)C=C1
• Target: Antibacterial,Antibiotic
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.58 mM);Ethanol:8 mg/mL (22.33 mM);DMSO:50 mg/mL (139.58 mM)

Bioactivity

• In Vivo:
  Florfenicol administers at doses of 15 and 20 mg FFC kg(-1) bw per days for 10 days significantly reduces mortality associated with francisellosis in Nile tilapia.
• In Vitro:
  Florfenicol is found to stimulate algal growth at concentrations of 0.5, 1.0 and 2.0 mg/L, and significantly inhibit algal growth at >2.0 mg/L.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SCH 25298, SCH25298, SCH-25298, Inhibitor, inhibit, Florfenicol, Bacterial, Antibiotic, 76639-94-6, (-)-Florfenicol

Compound Identifiers

PubChem CID

114811