Ferric maltol

SKU: orb1940750

Description

Ferric maltol is a ferric, non-salt-based oral iron formulation demonstrating improved tolerance in patients with previous intolerance to other iron formulations.(In Vitro):Ferric maltol increases transferrin saturation and levels of serum ferritin, serum iron, blood hemoglobin, and reticulocyte hemoglobin.(In Vivo):Iron that is not absorbed from Ferric maltol can remain in its chelated form at least throughout the small intestine, minimizing the risk of intestinal mucosal damage from free iron and potentially reducing local toxicity.

Key Properties

• CAS Number: 33725-54-1
• MW: 431.154
• Purity: >98% (HPLC)
• Formula: C₁₈H₁₅FeO₉
• SMILES: CC1=C2[O-][Fe+3]34([O-]C5=C(C)OC=CC5=[O]3)([O-]C3=C(C)OC=CC3=[O]4)[O]=C2C=CO1
• Target: Human Endogenous Metabolite
• Solubility: In Vitro: DMSO : 12.5 mg/mL (28.99 mM)

Bioactivity

• In Vivo:
  Animal studies show that iron that is not absorbed from Ferric maltol can remain in its chelated form at least throughout the small intestine, minimizing the risk of intestinal mucosal damage from free iron and potentially reducing local toxicity.
• In Vitro:
  The administration of Ferric maltol can increase transferrin saturation and levels of serum iron, serum ferritin, reticulocyte hemoglobin, and blood hemoglobin.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate

Quick Database Links

Gene Symbol

Human Endogenous Metabolite