FC131 TFA (606968-52-9 free base)

SKU: orb1296645

Description

FC131 TFA (CAS 606968-52-9) (free base) is a potent CXCR4 antagonist with an IC50 of 4.5 nM against SDF-1 binding. It exhibits anti-HIV activity and is used in research on cancer metastasis, stem cell mobilization, and inflammatory diseases in both cellular and animal models.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 842166-42-1
• MW: 843.85
• Purity: 99.67%
• Formula: C₃₈H₄₈F₃N₁₁O₈
• SMILES: FC(F)(F)C(=O)O.N=C(N)NCCC[C@@H]4NC(=O)[C@@H](NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](Cc2cc3ccccc3cc2)NC4=O)CCCNC(=N)N
• Target: HIV Protease,CXCR
• Solubility: DMSO:250 mg/mL (296.26 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (5.93 mM)

Bioactivity

• Target IC50:
  [125I]-SDF1-CXCR4:4.5 Nm

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

FC131 TFA, FC131 TFA (606968 52 9 free base), FC131 TFA (606968529 free base), FC-131 TFA (606968-52-9 free base), HIVProtease, HIV Protease, HIV, 606968-52-9, 606968-52-9 free base, CXCR4

Compound Identifiers

PubChem CID

71457332