Excisanin A

SKU: orb1682581

Description

Excisanin A is a bioactive small molecule that potently inhibits the AKT/NF-κB signaling pathway, suppressing MMP-2/9 expression and cancer cell invasion. It induces apoptosis in SW620 colon cancer cells and inhibits inflammatory mediators like NO and PGE2 in vitro, highlighting its potential for metastasis and cancer research.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 78536-37-5
• MW: 350.45
• Formula: C₂₀H₃₀O₅
• SMILES: CC1(C)CC[C@H](O)[C@@]2(C)[C@@H]3C[C@H](O)[C@@H]4[C@@H](O)[C@@]3([C@H](O)C[C@H]12)C(=O)C4=C
• Target: Src,Akt,FAK,GSK-3,PI3K,Integrin,PARP,NF-κB,Caspase,JNK,Wnt/beta-catenin,MMP,Prostaglandin Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

11772488