Ethylene dimethanesulfonate

SKU: orb1308821

Description

Ethylene dimethanesulfonate is a non-volatile alkylating ester that selectively induces apoptosis in Leydig cells (LCs). It is widely used as a research tool in reproductive biology and toxicology studies, particularly for investigating testicular function and germ cell regulation in both in vitro and in vivo models.

Research Area

Cell Biology

Key Properties

• CAS Number: 4672-49-5
• MW: 218.25
• Purity: 98.94% (May vary between batches)
• Formula: C₄H₁₀O₆S₂
• SMILES: CS(=O)(=O)OCCOS(C)(=O)=O
• Target: Apoptosis
• Solubility: DMSO:95 mg/mL (435.28 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (15.12 mM)

Bioactivity

• In Vivo:
  Ethylene dimethanesulfonate (subcutaneous injection; 75 mg/kg; 7 days) leads to sperm granuloma formation in rat anddisrupts epididymal function.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Apoptosis, Ethylene, Ethylene dimethanesulfonate, Inhibitor, inhibit

Compound Identifiers

PubChem CID

20796