ESC1002755

SKU: orb3134995

Description

ESC1002755 is an inhibitor of 17β-HSD10 with an IC50 of 19 nM. Notably enzyme-specific, ESC1002755 exhibits non-competitive inhibition against the cofactor NADH. At a concentration of 50 μM, it shows minimal cytotoxicity in HEK293 cells. It holds potential for research in Alzheimer's disease and hormone-dependent cancers such as prostate, bone, and colorectal cancers.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2915567-21-2
• MW: 383.89
• Formula: C₂₁H₁₈ClNO₂S
• SMILES: C(=O)(N1[C@@H](CCC1)C2=C(C=CC=C2)C3=CC(O)=CC=C3)C=4SC=CC4Cl
• Target: Dehydrogenase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Dehydrogenase