Epaminurad HCl

SKU: orb2281195

Description

Epaminurad HCl is a small molecule research compound that functions as a selective URAT1 inhibitor, promoting uric acid excretion. It is utilized in preclinical research for studying hyperuricemia and gout pathogenesis, with applications in both in vitro transporter assays and in vivo animal models of the disease.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1198153-46-6
• MW: 450.51
• Purity: 99.42%
• Formula: C₁₄H₁₁Br₂ClN₂O₃
• SMILES: Cl.O=C(C1=CC(Br)=C(O)C(Br)=C1)N2C=3C=NC=CC3OCC2
• Target: OAT

Bioactivity

• In Vivo:
  In tufted capuchin monkeys, Epaminurad HCl (0, 3, 10, and 30 mg/kg; orally, once a day, for 3 consecutive days) showed good uricosuric and urate-lowering effects at the lowest dose of 3 mg/kg.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

OAT1, OAT3, Epaminurad HCl(1198153-15-9 Free base), EpaminuradHCl(1198153159Freebase), UR-1102 HCl, URAT1, URC-102 HCl

Compound Identifiers

PubChem CID

44608228