Enrofloxacin

SKU: orb1307995

Description

Enrofloxacin (BAY-Vp2674) is a fluoroquinolone antibiotic developed for veterinary medicine, primarily used to treat bacterial infections in poultry. It serves as a key research tool for studying antibacterial efficacy in both in vitro assays and in vivo animal models of infection.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 93106-60-6
• MW: 359.39
• Purity: 99.43% (May vary between batches)
• Formula: C₁₉H₂₂FN₃O₃
• SMILES: O=C1C=2C(N(C=C1C(O)=O)C3CC3)=CC(=C(F)C2)N4CCN(CC)CC4
• Target: Antibiotic|||DNA/RNA Synthesis|||Antibacterial
• Solubility: DMSO:12 mg/mL (33.39 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.78 mM)

Bioactivity

• Target IC50:
  Mycoplasma bovis:0.312 μg/mL (MIC90)
• In Vivo:
  Enrofloxacin exhibits broad-spectrum antibacterial activity against both Gram-negative and Gram-positive bacteria. It functions by inhibiting bacterial DNA gyrase (type II topoisomerase), thereby blocking DNA supercoiling and DNA synthesis.
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BAY Vp 2674, BAY Vp2674, BAY Vp-2674, BAY-Vp2674, Antibiotic, Bacterial, DNASynthesis, DNA Synthesis, DNA synthesis, Endogenous Metabolite, Enrofloxacin, Inhibitor, Orthopoxvirus, PD 160788, PD160788, PD-160788, inhibit, RNASynthesis, RNA Synthesis

Compound Identifiers

PubChem CID

71188