Eniluracil

SKU: orb1299658

Description

Eniluracil (GW776C85) is an oral inhibitor of dihydropyrimidine dehydrogenase (DPD) that enables complete oral bioavailability of 5-fluorouracil (5-FU). It is used in research to study combination chemotherapy, predict pharmacokinetics, and investigate DPD's role in pyrimidine metabolism in both in vivo and in vitro models.

Key Properties

• CAS Number: 59989-18-3
• MW: 136.11
• Purity: 98.79%
• Formula: C₆H₄N₂O₂
• SMILES: O=c1[nH]cc(C#C)c(=O)[nH]1
• Target: Others
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (14.69 mM);DMSO:62.5 mg/mL (459.19 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

dihydropyrimidine dehydrogenase (DPD), combination, cancer, 5-fluorouracil, 5-FU, 5-Ethynyluracil, Inhibitor, Eniluracil, GW776C85, inhibit, tumor

Compound Identifiers

PubChem CID

43157