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EGFR T790M/L858R-IN-3

SKU: orb3133221

Description

EGFRT790M/L858R-IN-3 (compound B1) is an EGFRL858R/T790M inhibitor with an IC50 value of 13 nM. In H1975 cells, EGFRT790M/L858R-IN-3 demonstrates antitumor activity with an IC50 of 0.087 μΜ. Additionally, it inhibits cell migration in A549 cells and induces apoptosis in H1975 cells (cellapoptosis).

Research Area

Cell Biology

Images & Validation

Key Properties

FormulaC28H32ClN7O2S2
TargetEGFR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

EGFR T790M/L858R-IN-3 (orb3133221)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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