EGFR-IN-160

SKU: orb3027582

Description

EGFR-IN-160 is an EGFR inhibitor with IC50 values of 1.62, 0.49, and 0.98 μM for EGFRWT, EGFRT790M, and EGFRL858R/T790M/C797S, respectively. It can induce cell cycle arrest at the G2/M and S phases and apoptosis (Apoptosis) in NCI-H522 cells, demonstrating anticancer properties. Additionally, EGFR-IN-160 exhibits antioxidant activity against DPPH (IC50: 12.11 µM) and H2O2 (IC50: 8.89 µM).

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 2172879-84-2
• MW: 284.27
• Formula: C₁₅H₁₂N₂O₄
• SMILES: O=C1N=C(C=C(N1)C=2C=CC(O)=C(OC)C2)C=3OC=CC3
• Target: EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

EGFR