Efinaconazole

SKU: orb1305663

Description

Efinaconazole (KP-103) is a topical azole antifungal agent developed for onychomycosis research. It demonstrates potent in vitro activity against dermatophytes and has shown efficacy in clinical trials for treating fungal nail infections.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 164650-44-6
• MW: 348.39
• Purity: 97.52%
• Formula: C₁₈H₂₂F₂N₄O
• SMILES: C[C@@H](N1CCC(=C)CC1)C(O)(Cn1cncn1)c1ccc(F)cc1F
• Target: Antifungal
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.74 mM);DMSO:45 mg/mL (129.17 mM)

Bioactivity

• Target IC50:
  SM-110 (T. mentagrophytes):0.0039 ug/ml (MIC)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Antifungal, Efinaconazole, Fungal, Inhibitor, KP 103, KP103, KP-103, inhibit

Compound Identifiers

PubChem CID

112500563