EFdA-TP 3TEA

SKU: orb2893606

Description

EFdA-TP 3TEA is a salt form of the nucleoside analog EFdA-TP, functioning as a potent and selective HIV-1 reverse transcriptase inhibitor. Its multi-mechanistic action against reverse transcriptase, including delayed chain termination, contributes to a high barrier to drug resistance, making it a valuable tool for antiviral research in vitro.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 2736455-59-5
• MW: 836.76
• Purity: 97.22% (May vary between batches)
• Formula: C₃₀H₆₀FN₈O₁₂P₃
• SMILES: CCN(CC)CC.O=P(O)(O)OP(OP(OC[C@]1(O[C@H](C[C@@H]1O)N2C3=NC(F)=NC(N)=C3N=C2)C#C)(O)=O)(O)=O.CCN(CC)CC.CCN(CC)CC
• Target: Reverse Transcriptase

Bioactivity

• In Vitro:
  EFdA-TP 3TEA (0.05-10 μM, 15 minutes) can inhibit RT-catalyzed DNA synthesis in the form of ICT or DCT.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

EFdATP3TEA

Compound Identifiers

PubChem CID

175666816