EC0489

SKU: orb1707972

Description

EC0489 is a folate receptor (FR)-targeting small molecule-drug conjugate (SMDC) composed of folic acid linked to desacetyl vinblastine hydrazide. It is a research tool for studying targeted drug delivery in models of refractory or metastatic FR-positive cancers, applicable in both in vitro and in vivo experimental settings.

Research Area

Cell Biology

Key Properties

• CAS Number: 1096702-14-5
• MW: 2550.7
• Formula: C₁₁₁H₁₅₆N₂₂O₄₃S₂
• SMILES: [H][C@@]12N3CC[C@@]11c4cc(c(OC)cc4N(C)[C@@]1([H])[C@](O)([C@H](O)[C@]2(CC)C=CC3)C(=O)NNC(=O)OCCSSC[C@H](NC(=O)[C@H](CCC(=O)NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(=O)NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(=O)NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)NC(=O)CC[C@H](NC(=O)c1ccc(NCc2c[nH]c3nc(N)nc(=O)c3n2)cc1)C(O)=O)C(O)=O)[C@]1(C[C@@]2([H])C[N@](C[C@](O)(CC)C2)CCc2c1[nH]c1ccccc21)C(=O)OC |c:29|
• Target: Others,Antifolate

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168012219