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E3 Ligase Ligand-linker Conjugate 58

SKU: orb2566357

Description

E3 Ligase Ligand-linker Conjugate 58 is a thalidomide-based Cereblon (CRBN) recruiting moiety attached to a linker. It is a key intermediate for constructing PROTAC degraders, which are widely used in chemical biology and drug discovery research for targeted protein degradation in both cellular and in vivo studies.

Research Area

Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2229725-27-1
MW539.62
FormulaC28H37N5O6
SMILESO=C1N(C(=O)C=2C1=CC(=CC2)N3CCN(CC4CCN(C(OC(C)(C)C)=O)CC4)CC3)C5C(=O)NC(=O)CC5
TargetE3 Ligase Ligand-Linker Conjugates

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information