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E3 ligase Ligand 26

SKU: orb2564399

Description

E3 Ligase Ligand 26 is a cereblon (CRBN)-binding moiety used to construct PROTAC molecules, such as the SOS1 degrader Compd 10. This ligand enables targeted protein degradation, facilitating the study of SOS1-dependent signaling pathways in cancer research using both cellular and in vivo models.

Research Area

Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2911613-35-7
MW414.28
FormulaC18H11F5N2O4
SMILESO=C(OC=1C(F)=C(F)C(F)=C(F)C1F)C2=CC=C(C(=C2)N3C(=O)NC(=O)CC3)C
TargetLigands for E3 Ligase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information