Duocarmycin SA

SKU: orb1992875

Description

Duocarmycin SA is a highly potent, sequence-selective DNA alkylating agent with sub-nanomolar cytotoxicity. It exhibits synergistic antitumor activity with proton radiation against glioblastoma in vitro and has been investigated in various cancer research models, including in vivo studies for its therapeutic potential.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 130288-24-3
• MW: 477.47
• Formula: C₂₅H₂₃N₃O₇
• SMILES: C(=O)(N1C=2[C@]3([C@](C3)(C1)[H])C4=C(NC(C(OC)=O)=C4)C(=O)C2)C=5NC=6C(C5)=CC(OC)=C(OC)C6OC
• Target: ADC Cytotoxin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

115369