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DUB-IN-2

SKU: orb1309734

Description

DUB-IN-2

Research Area

Cell Biology, Molecular Biology, Protein Biochemistry

Images & Validation

Key Properties

CAS Number924296-19-5
MW275.26
Purity98.96% (May vary between batches)
FormulaC15H9N5O
SMILESCCO\N=C1/c2ccccc2-c2nc(C#N)c(nc12)C#N
TargetDUB
SolubilityDMSO:9.06 mg/mL (32.91 mM)

Bioactivity

Target IC50
USP8:0.28 μM
In Vitro
DUBs-IN-2 inhibits the viability of HCT116 colon cell line and PC-3 prostate cancer cell line with IC50 values of 0.5-1.5 μM.DUBs-IN-2 is a potent USP8 inhibitor with an IC50 of 0.28 μM, and has no effect on USP7, with an IC50 of >100 μM.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Deubiquitinase, DUB IN 2, DUBs, DUBIN2, DUB-IN-2, Inhibitor, inhibit, USP8
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 180.00
2 mg
$ 240.00
5 mg
$ 340.00
1 ml x 10 mM (in DMSO)
$ 350.00
10 mg
$ 470.00
25 mg
$ 740.00
50 mg
$ 1,030.00
100 mg
$ 1,400.00
DispatchUsually dispatched within 5-10 working days
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